A Review on: Synthetic and Herbal Approaches for the Treatment of Rheumatoid Arthritis an Autoimmune Disorder

• Abhijit Narendra Daf*

Abstract

Rheumatoid arthritis (RA) is a condition characterized by an autoimmune response. This disorder primarily affects multiple joints in the body and has a global impact, affecting numerous individuals worldwide. RA is a progressive, chronic illness that manifests in various stages. As the disease advances, joint deterioration worsens, ultimately leading to the loss of joint function. Additionally, RA can also impact other organs within the body. The development of RA is influenced by several factors, including environmental elements, age, weight, genetics, and lifestyle choices. Etiological factors such as autoantibodies, inflammatory mediators, and genes contribute to the onset of RA. Symptoms of this disease encompass swelling, pain, decreased appetite, joint inflammation, fatigue, and pericarditis. The primary objective of RA treatment is to alleviate pain and inflammation while preventing joint dysfunction and deformity. To achieve this, a variety of medications are utilized, including non-steroidal anti-inflammatory drugs, steroids, and disease-modifying anti-rheumatic drugs. However, the use of synthetic drugs is associated with potentially life-threatening side effects. Consequently, individuals seek alternative medicines for RA treatment. The focus of this study is to emphasize the utilization of herbal medicines for the benefit of RA patients. Herbal medicines and isolated phytoconstituents derived from herbal and synthetic drugs offer advantages such as affordability, accessibility, high patient acceptance, and minimal side effects. These medications also enhance the patient's overall condition and reduce stress. Numerous researchers have demonstrated the efficacy of herbal drugs and phytoconstituents in treating RA patients. Therefore, this study aims to raise awareness regarding the importance of increasing the utilization of herbal drugs for RA treatment.

Keywords

Rheumatoid Arthritis, Pathophysiology, Herbal Treatment of RA, Synthetic Treatment of Rheumatoid Arthritis, Synthetic Treatment of RA