A COMPREHENSIVE REVIEW OF CIPROFLOXACIN: CLINICAL PHARMACOLOGY

• Vijay Gaikwad*

Abstract

Ciprofloxacin, a fluoroquinolone antibiotic, has been a cornerstone in the treatment of various bacterial infections for decades. This review provides a comprehensive analysis of the pharmacology, clinical uses, efficacy, safety profile, and considerations associated with ciprofloxacin tablets. The pharmacological properties of ciprofloxacin, including its mechanism of action, spectrum of activity, and pharmacokinetics, are discussed. Clinical indications for ciprofloxacin use, ranging from respiratory and urinary tract infections to skin and soft tissue infections, are delineated, with emphasis on its efficacy compared to alternative antibiotics. Additionally, safety considerations, including common and serious adverse effects, contraindications, and drug interactions, are outlined. Special populations such as pediatric, geriatric, pregnant, and breastfeeding patients are addressed, along with dosing considerations and formulations available. By synthesizing evidence from clinical trials, post-marketing surveillance, and pharmacovigilance data, this review aims to provide clinicians and researchers with a comprehensive understanding of the role of ciprofloxacin tablets in contemporary medical practice, along with insights into optimizing its use while mitigating associated risks.

Keywords

Ciprofloxacin, Tablets, Clinical Pharmacology, Safety, Efficacy , Uses