A comprehensive review of advances in liposome based formulations for burns and diabetic wounds

• KATEREGGA ISMAEL,*  
• AMAR ABDALGADER EDRISS, ABUBAKER,  
• Yassin Babkir Elshiekh Mohamed

Abstract

Liposome-based preparations have come to be known as a promising approach for treating burns diabetic wounds and other serious life threatening wounds, because of their distinctive features and the potential to be applied in multiple ways. The paper constitutes in-depth analysis of recent development in the sphere of liposome technology usage in wound management. The article mainly concentrates on their use; for the purpose of accelerating wound healing, suppression of inflammation , prevention of infections, preventing amputation and quality adjusted living. We will present numerous liposomal preparations including carrier liposomes with a drug load, growth factor-laden liposomes, and liposomes with antimicrobial capacity indicating their action mode and performance in preclinical as well as clinical studies. Moreover, we also talk about the problems that liposomal wound therapies are related to concerning the drug stability, having a high level of scalability, and regulatory aspects. We note possible solutions of the mentioned problems .Taking advantage of the latest research findings the innovations in nanotechnology, this review is aimed at making clinicians and researchers apprehensive of the potentials of liposome-based formulations in burns and diabetic wounds, therefore providing a perspective for future research and clinical applications.

Keywords

liposomes , diabetic wounds, burns, liposomal carries, stability problems.