---

Analytical method development and validation of ornidazole by using uv spectroscopy

---

Original Article

Author Details : M. Jerubin Welsingh*, R. Xavier Arulappa, V. Shankarananth

Volume : 6, Issue : 1, Year : 2024

Article Page : 18-22

https://doi.org/10.18231/j.ctppc.2024.004

Suggest article by email

Get Permission

---

Abstract

The present research work discusses the development and validation of a UV spectrophotometric method for ornidazole. Simple, accurate and cost efficient spectrophotometric method has been developed for the estimation of ornidazole in pure drug form. The optimum conditions for the analysis of the drug were established. The maximum wavelength (? max) was found to be 430 nm. Beers law was obeyed in the concentration range of 1?g/mL. Calibration curves shows a linear relationship between the absorbance and concentration. Validation was performed according to ICH guidelines for Linearity, accuracy, precision, LOD (limit of detection) and LOQ (limit of quantification). The sample solution was stable up to 36 hours. The proposed method may be suitable for the analysis of ornidazole in drug formulation for quality control purposes.

Keywords: Pharmacopoeia, Ornidazole, LOQ (limit of quantification)

How to cite : Welsingh M J, Arulappa R X, Shankarananth V, Analytical method development and validation of ornidazole by using uv spectroscopy. Curr Trends Pharm Pharm Chem 2024;6(1):18-22

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.